Glucose?based carbon electrode for trace?level detection of acetaminophen

نویسندگان

چکیده

A highly sensitive electrochemical method for trace-level detection of acetaminophen (AMP) was employed using glucose-based carbon electrode (Gu/CPE) by cyclic voltammetry (CV) and differential pulse (DPV). Electrochemical properties AMP were well suited in 0.2 M phosphate buffer solution (PBS) pH 7.0 peak intensity at the Gu/CPE enhanced compared to bare paste electrode. Furthermore, different parameters, such as electrolyte, scan rate, accumulation time effects, investigated CV. The redox reaction quasi-reversible controlled a diffusion process with two protons electrons. As per DPV technique, lower limit (LOD) 3.72 × 10–8 over wide linearity range (0.6-9.0 µM) observed. excipient study demonstrates selectivity toward AMP. utilized quantify clinical pharmaceutical samples.

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ژورنال

عنوان ژورنال: Electrochemical science advances

سال: 2021

ISSN: ['2698-5977']

DOI: https://doi.org/10.1002/elsa.202100117